ITEM 7.01 REGULATION FD DISCLOSURE.

Comerica Incorporated ("Comerica") previously announced that Ralph W. Babb, Jr., Chairman and Chief Executive Officer of Comerica, will make a presentation at the Sandler O'Neill 2008 East Coast Financial Services Conference on Thursday, November 13, 2008, at the Ritz-Carlton Hotel in Palm Beach, Florida. Elizabeth S. Acton, Executive Vice President and Chief Financial Officer, and Dale E. Greene, Executive Vice President and Chief Credit Officer, also will participate. Comerica's presentation will begin at 7:45 a.m. ET. To access the live audio webcast, visit the "Investor Relations" area of Comerica's website at www.comerica.com. Replays will be available at the same location following the conference. A copy of the presentation slides, which will be discussed at that conference, is attached hereto as Exhibit 99.1.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS.

(d) Exhibits

99.1 Sandler O'Neill 2008 East Coast Financial Services Conference Presentation Slides

---