Item 1.01 Entry into a Material Definitive Agreement.

On October 22, 2008, Amgen Inc. ("Amgen" or the "Company") entered into a master services agreement (the "Agreement") with International Business Machines Corporation (the "Supplier") for information systems infrastructure services including electronic messaging systems, networks, helpdesk support for end users, physical information technology support, servers hosting applications, information systems hardware refresh, and evolution of methods, processes and technologies being used to provide information systems infrastructure services.

The term of the Agreement is five years with three one-year renewal options by the Company, for a total of an eight year term. The costs to the Company for the five year term are estimated to be $500 million with a full eight year term estimated to be $800 million. Among other rights to terminate the agreement for cause or change of control of the Supplier, the Company may terminate the Agreement at its convenience by paying Supplier certain termination fees with the amount of such fees dependent upon timing of the termination.

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