On October 9, 2008, BioDelivery Sciences International, Inc. issued a press release pertaining to the promotion of Niraj Vasisht, Ph.D. to Senior Vice President of Product Development and Chief Technical Officer. Dr. Vasisht will continue to report to Andrew L. Finn, Pharm.D., Executive Vice President of Product Development. A copy of the press release is attached to this Current Report as Exhibit 99.1.

(d) Exhibits

99.1   Press release, dated October 9, 2008, regarding the promotion of Dr.
       Vasisht to Senior Vice President of Product Development and Chief Technical
       Officer.

This Current Report on Form 8-K and the exhibits hereto may contain, among other things, certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including, without limitation, statements with respect to the Company's plans, objectives, expectations and intentions and other statements identified by words such as "may", "could", "would", "should", "believes", "expects", "anticipates", "estimates", "intends", "plans" or similar expressions. These statements are based upon the current beliefs and expectations of the Company's management and are subject to significant risks and uncertainties. Actual results may differ from those set forth in the forward-looking statements. These forward-looking statements involve certain risks and uncertainties that are subject to change based on various factors (many of which are beyond the Company's control).