On August 13, 2008, ARYx Therapeutics, Inc. reported its financial results for the three months ended June 30, 2008. A copy of the press release issued by ARYx on August 13, 2008 concerning the foregoing results is furnished herewith as Exhibit 99.1 and is incorporated herein by reference.

The press release is furnished and shall not be deemed "filed" for purposes of
Section 18 of the Securities Exchange Act of 1934, as amended, or subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended. The information contained herein and in the accompanying exhibit shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission made by ARYx, whether made before or after the date hereof, regardless of any general incorporation language in such filing.

(d) Exhibits

Exhibit Number                               Description
     99.1        Press release, dated August 13, 2008, entitled "ARYx Reports Second
                 Quarter 2008 Financial Results - Late-Stage Cardiovascular Programs
                 Expected To Yield Significant Milestones Over The Coming Quarters."