Item 1.02 Termination of a Material Definitive Agreement.

On August 8, 2008, Genoptix, Inc., a Delaware corporation ("Genoptix"), entered into a Termination of Lease (the "Agreement") with Blackmore Signal Hill, L.P. ("Blackmore"). Pursuant to the terms of the Agreement, Genoptix and Blackmore terminated the lease agreement, dated February 4, 2008, under which Blackmore previously leased to Genoptix 12,472 square feet of office space in Carlsbad, California (the "Lease"). The material terms of the Lease are described in Genoptix's Current Report on Form 8-K filed with the Securities and Exchange Commission on February 7, 2008. The Lease was terminated as contemplated by Genoptix's new lease agreement with Allen Joseph Blackmore, Trustee of the Blackmore Family Trust, Restated 1995 ("Allen Joseph"), an affiliate of Blackmore, pursuant to which Allen Joseph leases to Genoptix 42,948 square feet of office space in Carlsbad, California.

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