Item 5.03. Amendments to Articles of Incorporation or Bylaws; Change in
Fiscal Year.

On June 19, 2008, the Board of Directors of Applera Corporation (the "Company") approved amendments (collectively, the "Amendment") to Section 8 of the Company's By-laws, effective immediately.

Pursuant to the Amendment, Section 8 of the Company's By-laws has been revised to clarify that stockholders must comply with the advance notice provision therein in order to propose any business at annual meetings. The Amendment further provides that, in order to be timely, a stockholder's notice must be delivered to the Company not less than 90 nor more than 120 days prior to the anniversary date of the immediately preceding annual meeting of stockholders.
Section 8 of the Company's By-laws formerly provided that a stockholder's notice be delivered to the Company not less than 45 nor more than 75 days before the anniversary of the date on which the Company first mailed its proxy materials for the preceding year's annual meeting. In addition, the Amendment also deletes reference to Rule 14a-8 under the Securities Exchange Act of 1934, as amended. The Amendment also adds a requirement that a stockholder who makes a proposal or nominates a director must disclose any short position or hedging arrangement that he or his nominee has with respect to the Company's common stock.

Item 9.01. Financial Statement and Exhibits.

(d) Exhibits.

The following exhibits are filed with this Report:

Exhibit No. Description

3.1 By-laws of Applera Corporation, as amended through June 19, 2008

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