ITEM 7.01 REGULATION FD DISCLOSURE

On Tuesday, April 29, 2008, Comerica Incorporated will hold a series of investor meetings giving a presentation titled "San Francisco Roadshow." Elizabeth S. Acton, Executive Vice President and Chief Financial Officer, and Dale E. Greene, Executive Vice President and Chief Credit Officer, will participate. A copy of the presentation slides, which will be discussed at each investor meeting, is attached hereto as Exhibit 99.1.

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS

(d) Exhibits

99.1 San Francisco Roadshow Presentation Slides

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